Bone Cancer Research - Symptoms, Types, Treatment

Bone Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Bone Cancer, including details on symptoms, types, treatment.


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Palliative spinal reconstruction using cervical pedicle screws for metastatic lesions of the spine: a retrospective analysis of 32 cases.

Oda I, Abumi K, Ito M, Kotani Y, Oya T, Hasegawa K, Minami A

Department of Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan. odaitr@aol.com

STUDY DESIGN: A retrospective study. OBJECTIVES: To evaluate clinical outcomes of palliative spinal reconstruction using cervical pedicle screws in metastatic spine tumors. SUMMARY OF BACKGROUND DATA: No study to date has investigated the effectiveness of cervical pedicle screw fixation in metastatic lesions of the spine. METHODS: A total of 32 patients with metastatic spine tumors who underwent reconstructive surgery using cervical pedicle screws were reviewed. Four patients presented upper cervical lesions and 28 patients had subaxial lesions. All patients had intractable pain, 29 presented myelopathy, and 18 patients were nonambulatory. Combined anterior column reconstruction was considered in cases of life expectancy more than 2 years and anterior spinal cord compression that could not be solved by posterior decompression and kyphosis correction. Posterior fixation alone was performed in 25 patients, and posterior fixation combined with anterior column reconstruction was performed in 7 patients. RESULTS: The average postoperative survival period was 12.2 months. Neck pain was improved in all cases. Twenty-four (83%) of the 29 patients with spinal cord lesions presented neurologic improvement. Of 18 patients who were not ambulatory, 16 patients (89%) became ambulatory. Pain relief, neurologic function, and spinal stability were maintained throughout the survival period in 30 of 32 patients (94%). CONCLUSION: Spinal reconstruction using cervical pedicle screws improved spinal stability, pain, and neurologic function. These improvements were maintained throughout the survival period in 94% of the patients. Anterior column reconstruction could be avoided in 78% of the patients in spite of damaged anterior column.

Published 2 June 2006 in Spine, 31(13): 1439-44.
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