Bone Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Bone Cancer, including details on symptoms, types, treatment.

Office-based intralesional cidofovir injections for nasal septal papilloma: a pilot study.

Shemen LJ, Shnayder Y

Department of Otolaryngology, New York University School of Medicine, 233 East 69th Street, New York, NY 10021, USA. larrys@firstgate.net

OBJECTIVES: To determine if nasal septal papilloma is responsive to intralesional cidofovir injections. METHODS: Five adult males, ages 37 to 57, presented with nasal septal or columellar papilloma. Three lesions had been previously excised with the laser and recurred. The lesions were injected with cidofovir on a monthly basis until complete resolution or any residual lesion was excised afterwards with the laser. RESULTS: All patients achieved disease remission sustained over 10 to 24 months. Overall doses were much lower than those described for laryngeal papillomatosis and no toxic effects were observed. CONCLUSIONS: Office-based intralesional injections of cidofovir may show benefit in the treatment of nasal septal papilloma. EBM rating: C-4.

Published 3 July 2006 in Otolaryngol Head Neck Surg, 135(1): 149-51.
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